Where did Cain get his wife?

 
         The Bible teaches clearly that all human beings are descendants of Adam and 
       Eve-thus there had to be inter-marriage between brother and sister. There 
       would have been no risk of this causing harmful deformities in the offspring, 
       because mutations (accidental changes in the hereditary information) need time 
       to occur and accumulate in a population. Thus the first few generations would 
       have inherited perfect or near-perfect genes, largely undamaged by mutations. 
       In the pre-Flood world, harmful radiation from the sun and other cosmic 
       sources was considerably more filtered than it is in the post-Flood world. 
          
           Increased radiation and depletion of oxygen in the atmosphere (subsequent to 
       the lowering of the atmospheric pressure) may have contributed greatly to man's 
       rapid degeneration. With the passing of many centuries, many of these harmful, 
       degenerative changes became added to the human race, so by the time of 
          
           Moses it was absolutely necessary to have laws against incest, and these were 
       given to mankind (Leviticus 18-20). Today there would be even more chance 
       of deformity/disease in the offspring of such a union than in Moses's time. 
        Because of the long life-spans, Adam and Eve's descendants may have been 
       very numerous and widely dispersed before Cain even took a wife-that is, any 
       inhabitants of the land of Nod would have been descendants of Adam and Eve, 
       who had many sons and daughters. 

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http://www.answersingenesis.org/home/area/tools/cains_wife.asp


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